From: Terry S. Singeltary Sr.
Sent: Friday, April 26, 2013 9:20 AM
To: BSE-L BSE-L
Cc: info@indianawildlife.org ; dnrwebmaster@dnr.IN.gov ; s1@iga.in.gov ; s4@iga.in.gov ; h57@in.gov ; simpson@indianawildlife.org ; twardy@indianawildlife.org ; watson@indianawildlife.org ; h51@in.gov ; h75@in.gov ; h53@in.gov ; h46@in.gov ; h30@in.gov ; h54@in.gov ; h62@in.gov ; h69@in.gov ; h64@in.gov ; h17@in.gov ; h42@in.gov ; h56@in.gov ; nkelly@jg.net
Subject: INDIANA Republican State Sen. Travis Holdman Senate Bill 373 ag-gag WILL PUT HUMANS AT RISK
INDIANA Republican State Sen. Travis Holdman Senate Bill 373 ag-gag WILL PUT HUMANS AT RISK. here is proof ;
3
Indiana Senate Bill
Trespass and application fraud. Provides that a person who knowingly or
intentionally: (1) submits an application to a prospective employer to secure
employment; and (2) makes a false statement about a material fact or conceals a
material fact in the application in order to secure employment, commits
application fraud, a Class A misdemeanor. Provides that for the purposes of
criminal trespass, a person has been denied entry to property when the person
has been denied entry by means of a fence, wall, or other constructed barrier
that reasonably implies entry is prohibited. Provides that a person making a
false or misleading written statement with the intent to obtain employment is
excluded from the deception statute.
if they take these investigative type videos out of the factory farms, then this recall for one example i.e. Central Valley Meat Co, of years back, where our children across the USA were fed dead stock downer cows for some 4 years, the most high risk animal for the TSE prion disease, and other deadly pathogens, this recall would never have happened. you take the the video out of factory farms, and the wolf will always guard the hen house.
just say no to any bill that bans the investigative type reporting that protects the consumer. ...
Monday, April 22, 2013
North Carolina Senate bill S.B. 648 could be health risk and risk your children again to mad cow type disease BSE TSE prion disease
Letter: Senate bill could be health risk
http://downercattle.blogspot.com/2013/04/north-carolina-senate-bill-sb-648-could.html
Saturday, March 3, 2012
Iowa Legislature gives the green light for more dead stock downer cows to be fed to your children i.e. mad cow CJD
http://downercattle.blogspot.com/2012/03/iowa-legislature-gives-green-light-for.html
don’t forget the children...
PLEASE be aware, for 4 years, the USDA fed our children all across the Nation (including TEXAS) dead stock downer cows, the most high risk cattle for BSE aka mad cow disease and other dangerous pathogens.
who will watch our children for CJD for the next 5+ decades ???
WAS your child exposed to mad cow disease via the NSLP ???
SCHOOL LUNCH PROGRAM FROM DOWNER CATTLE UPDATE
http://downercattle.blogspot.com/2009/05/who-will-watch-children.html
http://downercattle.blogspot.com/
DID YOUR CHILD CONSUME SOME OF THESE DEAD STOCK DOWNER COWS, THE MOST HIGH RISK FOR MAD COW DISEASE ???
you can check and see here ;
http://www.fns.usda.gov/fns/safety/pdf/Hallmark-Westland_byState.pdf
see more here ;
Wednesday, August 22, 2012
USDA, McDonald's suspend slaughterhouse buys from Central Valley Meat Co. over deadstock downer cows
http://downercattle.blogspot.com/2012/08/usda-mcdonalds-suspend-slaughterhouse.html
Wednesday, March 14, 2012
PINK SLIME, MRM’s, BSE AKA MAD COW DISEASE, AND THE USDA NSLP
http://madcowusda.blogspot.com/2012/03/pink-slime-mrms-bse-aka-mad-cow-disease.html
Saturday, April 21, 2012
HISD seeks refund on burgers with 'pink slime'
http://downercattle.blogspot.com/2012/04/hisd-seeks-refund-on-burgers-with-pink.html
Thursday, September 13, 2012
ABC NEWS SLIMED BY BPI OVER LFTB SCAM
http://madcowusda.blogspot.com/2012/09/abc-news-slimed-by-bpi-over-lftb-scam.html
Friday, April 19, 2013
FDA BSE TSE PRION NEWS FEED AND ANNUAL INSPECTION OF FEED MILLS REPORTS HAS CEASED TO EXIST
http://madcowusda.blogspot.com/2013/04/fda-bse-tse-prion-news-feed-and-annual.html
Monday, March 25, 2013
Minnesota Firm Recalls Bone-In Ribeye That May Contain Specified Risk Materials Recall Release CLASS II RECALL FSIS-RC-024-2013
http://madcowusda.blogspot.com/2013/03/minnesota-firm-recalls-bone-in-ribeye.html
Saturday, December 15, 2012
Bovine spongiform encephalopathy: the effect of oral exposure dose on attack rate and incubation period in cattle -- an update 5 December 2012
http://bse-atypical.blogspot.com/2012/12/bovine-spongiform-encephalopathy-effect.html
Tuesday, March 5, 2013
Use of Materials Derived From Cattle in Human Food and Cosmetics; Reopening of the Comment Period FDA-2004-N-0188-0051 (TSS SUBMISSION)
FDA believes current regulation protects the public from BSE but reopens comment period due to new studies
http://transmissiblespongiformencephalopathy.blogspot.com/2013/03/use-of-materials-derived-from-cattle-in_6452.html
Wednesday, March 20, 2013
GAO-13-244, Mar 18, 2013 Dietary Supplements FDA May Have Opportunities to Expand Its Use of Reported Health Problems to Oversee Product
From: Terry S. Singeltary Sr.
Sent: Tuesday, March 19, 2013 2:46 PM
To: gomezj@gao.gov
Cc: siggerudk@gao.gov ; youngc1@gao.gov ; oighotline@gao.gov
http://transmissiblespongiformencephalopathy.blogspot.com/2013/03/gao-13-244-mar-18-2013-dietary.html
Wednesday, February 20, 2013
World Organization for Animal Health Recommends United States' BSE Risk Status Be Upgraded
Statement from Agriculture Secretary Tom Vilsack:
http://madcowusda.blogspot.com/2013/02/world-organization-for-animal-health.html
Thursday, February 14, 2013
The Many Faces of Mad Cow Disease Bovine Spongiform Encephalopathy BSE and TSE prion disease
http://bse-atypical.blogspot.com/2013/02/the-many-faces-of-mad-cow-disease.html
Friday, April 19, 2013
Bovine Spongiform Encephalopathy (BSE) Feed Safety Support Program Grants Fiscal Year 2011: October 1, 2010 - September 30, 2011 FDA
http://madcowusda.blogspot.com/2013/04/bovine-spongiform-encephalopathy-bse.html
Dissociation between Transmissible Spongiform Encephalopathy (TSE) Infectivity and Proteinase K-Resistant PrPSc Levels in Peripheral Tissue from a Murine Transgenic Model of TSE Disease
Karen Dobie and Rona Barron
+ Author Affiliations
Neurobiology Division, The Roslin Institute & R(D)SVS, Easter Bush, Midlothian, United Kingdom
ABSTRACT
Most current diagnostic tests for transmissible spongiform encephalopathies (TSE) rely on the presence of proteinase K (PK)-resistant PrPSc (PrP-res) in postmortem tissues as an indication of TSE disease. However, a number of studies have highlighted a discrepancy between TSE infectivity and PrP-res levels in both natural and experimental cases of TSE disease. Previously, we have shown high TSE infectivity levels in the brain tissue of mice that have a clinical TSE disease with associated vacuolar pathology but little or no detectable PrP-res. Here, the levels of TSE infectivity and PrP-res within a peripheral tissue of this mouse model were investigated. Biochemical analysis showed that low levels of PrP-res were present in the spleen tissue in comparison to the levels observed in the spleen of mice infected with ME7 or 79A. However, upon subpassage of brain and spleen tissue from clinically ill mice with little or no PrP-res detectable, similar short incubation periods to disease were observed, indicating that infectivity levels were similarly high in both tissues. Thus, the discrepancy between PrP-res and TSE infectivity was also present in the peripheral tissues of this disease model. This result indicates that peripheral tissues can contain higher levels of infectivity given the correct combination of host species, PrP genotype, and TSE agent. Therefore, the assumption that the levels of peripheral infectivity are lower than those in the central nervous system is not always correct, and this could have implications for current food safety regulations.
FOOTNOTES
Received 19 December 2012.
Accepted 7 March 2013.
Address correspondence to Rona Barron, rona.barron@roslin.ed.ac.uk.
Published ahead of print 13 March 2013
Copyright © 2013, American Society for Microbiology. All Rights Reserved.
http://jvi.asm.org/content/87/10/5895.abstract?etoc
> and this could have implications for current food safety regulations.
now that’s funny, I don’t care who you are.
if for one minute anyone thinks any government regulatory body i.e. the USDA, CFIA, MAFF, and or the OIE, is going to change any regulatory aspects of the BSE TSE SRM tissue regulations, if anyone believes this, I have some beach front property out in west Texas up for sale...
Wednesday, April 24, 2013
Dissociation between Transmissible Spongiform Encephalopathy (TSE) Infectivity and Proteinase K-Resistant PrPSc Levels in Peripheral Tissue from a Murine Transgenic Model of TSE Disease
http://transmissiblespongiformencephalopathy.blogspot.com/2013/04/dissociation-between-transmissible.html
Friday, April 19, 2013
FDA BSE TSE PRION NEWS FEED AND ANNUAL INSPECTION OF FEED MILLS REPORTS HAS CEASED TO EXIST
http://madcowusda.blogspot.com/2013/04/fda-bse-tse-prion-news-feed-and-annual.html
Saturday, December 15, 2012
Bovine spongiform encephalopathy: the effect of oral exposure dose on attack rate and incubation period in cattle -- an update 5 December 2012
http://bse-atypical.blogspot.com/2012/12/bovine-spongiform-encephalopathy-effect.html
Tuesday, March 5, 2013
Use of Materials Derived From Cattle in Human Food and Cosmetics; Reopening of the Comment Period FDA-2004-N-0188-0051 (TSS SUBMISSION)
FDA believes current regulation protects the public from BSE but reopens comment period due to new studies
http://transmissiblespongiformencephalopathy.blogspot.com/2013/03/use-of-materials-derived-from-cattle-in_6452.html
Wednesday, February 20, 2013
World Organization for Animal Health Recommends United States' BSE Risk Status Be Upgraded
Statement from Agriculture Secretary Tom Vilsack:
http://madcowusda.blogspot.com/2013/02/world-organization-for-animal-health.html
Thursday, February 14, 2013
The Many Faces of Mad Cow Disease Bovine Spongiform Encephalopathy BSE and TSE prion disease
http://bse-atypical.blogspot.com/2013/02/the-many-faces-of-mad-cow-disease.html
http://madcowusda.blogspot.com/
Thursday, February 21, 2013
National Prion Disease Pathology Surveillance Center Cases Examined January 16, 2013
http://prionunitusaupdate2008.blogspot.com/2013/02/national-prion-disease-pathology.html
16 YEAR OLD SPORADIC FFI ?
Monday, January 14, 2013
Gambetti et al USA Prion Unit change another highly suspect USA mad cow victim to another fake name i.e. sporadic FFI at age 16 CJD Foundation goes along with this BSe
http://transmissiblespongiformencephalopathy.blogspot.com/2013/01/gambetti-et-al-usa-prion-unit-change.html
Monday, December 31, 2012
Creutzfeldt Jakob Disease and Human TSE Prion Disease in Washington State, 2006–2011-2012
http://creutzfeldt-jakob-disease.blogspot.com/2012/12/creutzfeldt-jakob-disease-and-human-tse.html
Tuesday, December 25, 2012
CREUTZFELDT JAKOB TSE PRION DISEASE HUMANS END OF YEAR REVIEW DECEMBER 25, 2012
http://creutzfeldt-jakob-disease.blogspot.com/2012/12/creutzfeldt-jakob-tse-prion-disease.html
Tuesday, June 26, 2012
Creutzfeldt Jakob Disease Human TSE report update North America, Canada, Mexico, and USDA PRION UNIT as of May 18, 2012
type determination pending Creutzfeldt Jakob Disease (tdpCJD), is on the rise in Canada and the USA
http://creutzfeldt-jakob-disease.blogspot.com/2012/06/creutzfeldt-jakob-disease-human-tse.html
Wednesday, June 13, 2012
MEXICO IS UNDER or MIS DIAGNOSING CREUTZFELDT JAKOB DISEASE AND OTHER PRION DISEASE SOME WITH POSSIBLE nvCJD
http://creutzfeldt-jakob-disease.blogspot.com/2012/06/mexico-is-under-or-mis-diagnosing.html
*** The discovery of previously unrecognized prion diseases in both humans and animals (i.e., Nor98 in small ruminants) demonstrates that the range of prion diseases might be wider than expected and raises crucial questions about the epidemiology and strain properties of these new forms. We are investigating this latter issue by molecular and biological comparison of VPSPr, GSS and Nor98.
VARIABLY PROTEASE-SENSITVE PRIONOPATHY IS TRANSMISSIBLE ...price of prion poker goes up again $
OR-10: Variably protease-sensitive prionopathy is transmissible in bank voles
Romolo Nonno,1 Michele Di Bari,1 Laura Pirisinu,1 Claudia D’Agostino,1 Stefano Marcon,1 Geraldina Riccardi,1 Gabriele Vaccari,1 Piero Parchi,2 Wenquan Zou,3 Pierluigi Gambetti,3 Umberto Agrimi1 1Istituto Superiore di Sanità; Rome, Italy; 2Dipartimento di Scienze Neurologiche, Università di Bologna; Bologna, Italy; 3Case Western Reserve University; Cleveland, OH USA
Background. Variably protease-sensitive prionopathy (VPSPr) is a recently described “sporadic”neurodegenerative disease involving prion protein aggregation, which has clinical similarities with non-Alzheimer dementias, such as fronto-temporal dementia. Currently, 30 cases of VPSPr have been reported in Europe and USA, of which 19 cases were homozygous for valine at codon 129 of the prion protein (VV), 8 were MV and 3 were MM. A distinctive feature of VPSPr is the electrophoretic pattern of PrPSc after digestion with proteinase K (PK). After PK-treatment, PrP from VPSPr forms a ladder-like electrophoretic pattern similar to that described in GSS cases. The clinical and pathological features of VPSPr raised the question of the correct classification of VPSPr among prion diseases or other forms of neurodegenerative disorders. Here we report preliminary data on the transmissibility and pathological features of VPSPr cases in bank voles.
Materials and Methods. Seven VPSPr cases were inoculated in two genetic lines of bank voles, carrying either methionine or isoleucine at codon 109 of the prion protein (named BvM109 and BvI109, respectively). Among the VPSPr cases selected, 2 were VV at PrP codon 129, 3 were MV and 2 were MM. Clinical diagnosis in voles was confirmed by brain pathological assessment and western blot for PK-resistant PrPSc (PrPres) with mAbs SAF32, SAF84, 12B2 and 9A2.
Results. To date, 2 VPSPr cases (1 MV and 1 MM) gave positive transmission in BvM109. Overall, 3 voles were positive with survival time between 290 and 588 d post inoculation (d.p.i.). All positive voles accumulated PrPres in the form of the typical PrP27–30, which was indistinguishable to that previously observed in BvM109 inoculated with sCJDMM1 cases.
In BvI109, 3 VPSPr cases (2 VV and 1 MM) showed positive transmission until now. Overall, 5 voles were positive with survival time between 281 and 596 d.p.i.. In contrast to what observed in BvM109, all BvI109 showed a GSS-like PrPSc electrophoretic pattern, characterized by low molecular weight PrPres. These PrPres fragments were positive with mAb 9A2 and 12B2, while being negative with SAF32 and SAF84, suggesting that they are cleaved at both the C-terminus and the N-terminus. Second passages are in progress from these first successful transmissions.
Conclusions. Preliminary results from transmission studies in bank voles strongly support the notion that VPSPr is a transmissible prion disease. Interestingly, VPSPr undergoes divergent evolution in the two genetic lines of voles, with sCJD-like features in BvM109 and GSS-like properties in BvI109.
The discovery of previously unrecognized prion diseases in both humans and animals (i.e., Nor98 in small ruminants) demonstrates that the range of prion diseases might be wider than expected and raises crucial questions about the epidemiology and strain properties of these new forms. We are investigating this latter issue by molecular and biological comparison of VPSPr, GSS and Nor98.
http://www.landesbioscience.com/journals/prion/01-Prion6-2-OralPresentations.pdf?nocache=1216084967
Wednesday, March 28, 2012
VARIABLY PROTEASE-SENSITVE PRIONOPATHY IS TRANSMISSIBLE, price of prion poker goes up again $
http://prionopathy.blogspot.com/2012/03/variably-protease-sensitve-prionopathy.html
Sunday, March 31, 2013
Creutzfeldt Jakob Disease CJD worlds youngest documented victim, 11 years old, shall we pray
http://creutzfeldt-jakob-disease.blogspot.com/2013/03/creutzfeldt-jakob-disease-cjd-worlds.html
Monday, April 15, 2013
Dr. Stephen B. Thacker Director Centers for Disease Control and Prevention′s Office of Science, Epidemiology and Laboratory Services (OSELS) dies from Creutzfeldt Jakob Disease CJD
http://creutzfeldt-jakob-disease.blogspot.com/2013/04/dr-stephen-b-thacker-director-centers.html
TSS
Wednesday, April 24, 2013
factory farming and the banning of investigative type video reporting is just plain stupid
http://downercattle.blogspot.com/2013/04/factory-farming-and-banning-of.html
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