Tuesday, March 11, 2014

Two cases of mad cow disease detected at farm in central Greece imported from the Netherlands

UPDATE, GOOD NEWS. apparently, these recent cases of mad cow disease in Greece, supposedly from the Netherlands, were false positives...see ;



 
Sent: Saturday, April 12, 2014 2:47 PM
Subject: RE: 319548.00 FW: Bovine Spongiform Encephalopathy BSE
 

 
 
Geachte Mr TS Singeltary,
 
 
Op 17-03-2014  heeft de NVWA een vraag van u ontvangen.

 ****
Concerning ProMED-mail post "BSE, bovine - Greece: (TC) susp, RFI 20140312.2329623," both cases were not confirmed by the European Reference Lab last week:
 
They were false positives.
 
[The above information refers to brain material from 2 cows, thought to be 6 years old, reportedly found dead on a farm in Fthiotida [Phthiotis], Central Greece, probably during the week of 10 Mar 2014.
 
See commentary in the posting.
If CNS symptoms had been observed in the affected cows prior to their deaths, rabies (currently circulating in Greece) deserved to be included among the differential diagnoses. - Mod.AS]
 
[See Also:
BSE, bovine - Greece: (TC) susp, RFI 20140312.2329623] .....................arn/msp/dk
****           

Hopende u hiermee voldoende te hebben geïnformeerd.
Carla Aponno
hoofd afdeling Klantcontactcentrum
........................................................................
Divisie Klantcontact & dienstverlening
Nederlandse Voedsel- en WarenautoriteitCatharijnesingel 59 | 3511 GG | Utrecht
Postbus 43006 | 3540 AA | Utrecht
........................................................................
T 0900-0388info@nvwa.nl
http://www.nvwa.nl
De NVWA streeft ernaar continu haar dienstverlening te verbeteren. Daarom zijn we heel benieuwd naar hoe u dit mailcontact hebt ervaren. Wilt u ons helpen door mee te doen met een kort online onderzoek? Door hier te klikken, opent zich een online vragenlijst met vijf vragen. Alvast bedankt.
 
 
Van: flounder9@verizon.net [mailto:flounder9@verizon.net]
Verzonden: maandag 17 maart 2014 11:59
Aan: NVWA Klantcontactcentrum
Onderwerp: 319548.00 ERNA FW: Bovine Spongiform Encephalopathy BSE
Uw kenmerk is E3117443
 
Geachte collega,
 
Er is bij Informatie Rijksoverheid een e-mail binnengekomen waarvoor wij uw medewerking nodig hebben. Zou u onderstaand bericht willen beantwoorden?
 
Bij voorbaat dank.
 
Met vriendelijke groet,
 
Angela Delvers
Publieksvoorlichter Informatie Rijksoverheid
 


end...TSS



is it still a spontaneous happening, when two cows go down with BSE on one farm ???

 
wonder if they were typical or atypical cases ???


Two cases of mad cow disease in Central Greece; animals imported from the Netherlands

 
Tuesday, March 11, 2014 6:06

 
A farm in Fthiotida, central Greece, has been placed in quarantine after two cases of mad cow disease were discovered there, almost 10 years since the disease last appeared in Greece.

 
The cases of bovine spongiform encephalopathy (BSE) were found in two dead cows that had been imported from the Netherlands. The animals are thought to be six years old.

 
No information was available about when the animals were imported from the Netherlands.

 
BSE can be transmitted to humans who eat food derived from the infected cows, particularly if it contains nervous tissue. In humans, the disease is known as new variant Creutzfeldt–Jakob disease.

 
Greek Agriculture Ministry said that the farm has been closed off and further tests are being carried out, while a ban on entry and exit of animals and their products from the affected farm has been imposed.

 
The package of measures issued by the Agriculture Ministry includes also:

 
1. briefing of the farmer and involved stakeholders for mandatory compliance of all necessary measures to combat the disease.

 
2. strengthening and intensification of officials inspections and controls of carcasses in slaughterhouses and compulsorily tests for possible presence of the disease before meat and meat-products are given for consumption.

 
3. Briefing the European Commission on the cases.

 
BSE can be transmitted to humans who eat food derived from the infected cows, particularly if it contains nervous tissue. In humans, the disease is known as new variant Creutzfeldt–Jakob disease.

 
sources: ekathimerini, skai.gr

 


 


 

Two cases of mad cow disease detected at farm in central Greece

 
A farm in Fthiotida, central Greece, has been placed in quarantine after two cases of mad cow disease were discovered there, almost 10 years since the disease last appeared in Greece.

 
The cases of bovine spongiform encephalopathy (BSE) were found in two dead cows that had been imported from the Netherlands. The animals are thought to be six years old.

 
BSE can be transmitted to humans who eat food derived from the infected cows, particularly if it contains nervous tissue. In humans, the disease is known as new variant Creutzfeldt–Jakob disease.

 
The Agriculture Ministry said that the farm has been closed off and further tests are being carried out. ekathimerini.com , Tuesday March 11, 2014 (10:18)

 
http://www.ekathimerini.com/4dcgi/_w_articles_wsite1_1_11/03/2014_538057



 

From:
 
Copyright/License ►Request permission to reuse

Table 1.

Details of Austrian and Dutch BSE cases until March 2011a
Case no. Yr of birth Age (mo) Screening testb Confirmation testc Status at death Typing resultd
AU01 1996 70 PCW OIE-WB Healthy C (A1B2)
AU02 1994 134 TeSeE OIE-WB Healthy C (A1B2)
AU03 1992 155 LIA IHC Healthy C (A1B2)
AU04 2000 70 LIA IHC Healthy C (A1B2)
AU05 1993 149 LIA OIE-WB Fallen st. CP4 (A2B2)
AU06 1996 130 LIA IHC Fallen st. L (A4B1)
AU07 1997 150 PCP Bio-Rad-WB Healthy L (A4B1)
AU08 1995 180 PCP Bio-Rad-WB Fallen st. H (A2B4)
NL73 1996 91 PCW IHC Healthy C (A1B2)
NL74 1996 90 PCW IHC Healthy C (A1B2)
NL86 1999 140 PS IHC Healthy C (A1B2)
NL87 1997 162 PCW IHC Fallen st. C (A1B2)
NL88 1996 174 PCW IHC Fallen st. L (A4B1)
 
aAll Austrian cases were investigated for the type of BSE for the first time, as well as the most recent Dutch cases (NL86 to -88), plus some confirmed C BSE cases from a previous study (NL73, NL74) in which all Dutch cases had been analyzed (15). Fallen st., fallen stock (i.e., animals that died on the farm).
 
bPCW = Prionics-Check Western blot; TeSeE = enzyme-linked immunosorbent assay (ELISA)-like Bio-Rad TeSeE test; LIA = ELISA-like Prionics-Check luminescence immunoassay; PCP = immunochromatographic lateral diffusion Prionics-Check PrioSTRIP test; PS = Roche PrionScreen ELISA-like test.
 
cOIE-WB = World Organisation for Animal Health (OIE)-recognized methods using scrapie-associated fibril (SAF) purification and Western blot detection; IHC = OIE-recognized method using immunohistochemistry; Bio-Rad-WB = an EU-recognized PrPres preparation method, followed by Western blotting.
 
dTyping results (and classifications, shown in parentheses) were derived from Fig. 1. AU05 is a C-type BSE case with intermediately high MAb 12B2 reactivity and unusually high MAb P4 binding comparable to that of 12B2. Such high P4 affinity has not been observed previously, neither for intact bovine PrP nor its fragments (Fig. 2).
 
 
J Clin Microbiol. Aug 2011; 49(8): 3026–3028.
PMCID: PMC3147744
Notes

Four Independent Molecular Prion Protein Parameters for Discriminating New Cases of C, L, and H Bovine Spongiform Encephalopathy in Cattle[down-pointing small open triangle]

Jan P. M. Langeveld,1,* Jo H. F. Erkens,1 Ines Rammel,2 Jorg G. Jacobs,1 Aart Davidse,1 Fred G. van Zijderveld,1 Alex Bossers,1 and Hermann Schildorfer2
 
 
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147744/
 
 
 ALSO SEE OIE ON BSE CASES IN THE NETHERLANDS ;
 
 

Number of reported cases of bovine spongiform encephalopathy (BSE)
in farmed cattle worldwide* (excluding the United Kingdom)

 
Country/Year
 
89
 
90
 
91
92
 
93
 
94
 
95
 
96
 
97
 
98
 
99
 
 
00
 
 
 
 
01
 
 
 
 
02
 
 
 
 
03
 
 
 
 
04
 
 
05
06
07
08
09
10
11
12
13
14
 
Netherlands
 
 
0
 
0
 
0
 
0
 
0
 
0
 
0
 
0
 
2
 
2
 
2
 
2
 
20
 
24
 
19
6
3
2
2
1
0
2
1m
0
0
 


m
Netherlands year 2011 - Atypical BSE case (L-type).

 
http://www.oie.int/animal-health-in-the-world/bse-specific-data/number-of-reported-cases-worldwide-excluding-the-united-kingdom/


 
Opinion of the Scientific Steering Committee on the GEOGRAPHICAL RISK OF BOVINE SPONGIFORM ENCEPHALOPATHY (GBR) in GREECE Adopted by the SSC on 6 December 2002

 


 

MONITORING AND ERADICATION PROGRAMME OF TSE, BSE AND SCRAPIE APPROVED* FOR 2009 BY COMMISSION DECISION 2008/897/EC GREECE

 

snip...

 

CONCLUSION ON THE CURRENT GBR

 

The BSE-agent was most likely imported into the country and could have reached domestic cattle via cross-contamination in feed mills, during transport or on farm. It is therefore concluded that it is likely that one or several cattle infected (pre-clinically or clinically) with the BSE agent are currently in the domestic cattle population of Greece (GBR III). This is confirmed by the domestic case identified in 2001.

 

EXPECTED DEVELOPMENT OF THE GBR

 

As long as the system remains neutrally stable, the probability of cattle to be pre-clinically or clinically infected with the BSE-agent will remain but will not grow anymore even if the external challenge continues to be at such a high level as in the past.

 

A table summarising the reasons for the current assessment is given in annex 1 to this opinion. A detailed report on the assessment of the GBR of Greece as produced by the GBR-Peer Group is published separately on the Internet. The country had opportunities to comment on different drafts of the report before the SSC took both, the report and the comments, into account for producing this opinion. The SSC appreciates the good co-operation of the country’s authorities.

 


 

Report on the Assessment of the Geographical BSE-Risk (GBR) of THE NETHERLANDS July 2000

 


 

Netherlands BSE GBR III

 

40. Netherlands III (07/2000) -

 


 

that’s what I call one heck of a spontaneous event, two BSE cases on one farm...tss

 

Increased incidence of sporadic Creutzfeldt-Jakob disease on the island of Crete associated with a high rate of PRNP 129-methionine homozygosity in the local population

 

Andreas Plaitakis MD1,*, Anna K. Viskadouraki MD1, Minas Tzagournissakis MD1, Ioannis Zaganas MD1, Susan Verghese-Nikolakaki PhD2, Vasilis Karagiorgis2, Ioannis Panagiotides MD3, Constantine Kilindireas MD4, Eustratios Patsouris MD5, Christine Haberler MD6, Herbert Budka MD6, Theodoros Sklaviadis PhD2

 

Article first published online: 15 NOV 2001

 

DOI: 10.1002/ana.1285

 

Copyright © 2001 Wiley-Liss, Inc.

 

Issue

 

Annals of Neurology

 

Volume 50, Issue 2, pages 227–233, August 2001

 

 SEARCH

 
 

 Abstract

 

Since the spring of 1997, when the Neurology Department of the University Hospital of Crete admitted its first patient, 9 cases (8 neuropathologically confirmed and 1 probable) of sporadic Creutzfeldt-Jakob disease (sCJD) have been recorded. This represents an annual incidence five-fold higher than expected based on the island's population (0.54 million). Molecular analysis of the prion-protein gene (PRNP) showed no mutations in any of the seven CJD cases studied. Five patients (ages 64–88 years) were homozygous for methionine-129 of PRNP and showed the classic sCJD triad (subacute dementia, myoclonus, periodic electroencephalogram). Brains contained Type 1 (unglycosylated 21.5 kDa band) protease-resistant prion protein (PrPres). Two patients (ages 56 and 57 years), both homozygous for valine-129, showed cerebellar ataxia and later dementia not associated with periodic electroencephalogram; brain PrPres was Type 2. Genotyping of 205 Cretan controls showed that methionine-129 homozygosity, a susceptibility factor for sCJD, was significantly higher in this population than in other Caucasian populations (57.0%, n = 205 versus 41.5%, n = 859. These data are the first to relate a high regional incidence rate for sCJD to the distribution of PRNP 129 genotypes in the local population; however, additional factors may be operational.

 


 

Monday, February 02, 2009

Netherlands reports third human death from mad cow disease

http://creutzfeldt-jakob-disease.blogspot.com/2009/02/netherlands-reports-third-human-death.html


Panencephalopathic Creutzfeldt–Jakob disease in the Netherlands and the UK: clinical and pathological characteristics of nine patients C. Jansen1, M. W. Head2, A. J. M. Rozemuller1, J. W. Ironside2 Article first published online: 29 APR 2009

 

DOI: 10.1111/j.1365-2990.2008.01004a.x

 

Keywords:Creutzfeldt–Jakob disease;panencephalopathic type;prion diseases;prion protein;Western blot;white matterAims: The panencephalopathic type of Creutzfeldt–Jakob disease (PECJD) has extensive abnormalities in cerebral white matter as well as the cortex. PECJD has rarely been described in Caucasians and debate continues on its classification and pathogenesis. We describe our experience of PECJD over a 14-year period of surveillance for CJD in the Netherlands and the UK. Methods: Between 1993 and 2006, nine cases of PECJD were identified. Clinical, histological and biochemical characteristics of all patients were analysed and compared; all cases were classified clinically as sporadic CJD. Results: The median age at onset was 57.8 years and median disease duration was 22 months. The average brain weight was 887 g. Most patients showed a two-stage clinical course with initial rapid deterioration to a state of akinetic mutism, which then persisted over a longer time scale. Neuropathological findings were characterized by severe global atrophy with status spongiosus. Cerebral white matter involvement tended to be associated with either disease duration or severity of cerebral cortical lesions. Five patients could be classified into the MM1 subtype of sporadic CJD, one patient into the MM2 subgroup and another into the MV2 subgroup. Two patients were heterozygous at codon 129 in the prion protein gene and contained both type 1 and type 2 PrPres isoforms in the brain.

 

Conclusions: We believe that white matter pathology in PECJD represents an end-stage pattern that reflects secondary degeneration due to widespread cortical neuronal loss that occurs in the early part of the disease, rather than representing a primary lesion.

 


 

Monday, March 10, 2014

 

Investigators study silent variant of mad cow disease Galveston Daily News March 4, 2014

 


 

exactly why the OIE and USDA INC DO NOT go by the BSE GBR risk assessments anymore, going to a BSE Minimal Risk Region i.e. BSE MRR, the legal trading of the TSE prion globally. this happening ONLY after that infamous day in December 23, 2003, when the BSE science was changed to BSE junk science, thanks to the USDA INC and the OIE $$$ eat up, dead stock downers, cancer cows, and now LSD cows, it’s what’s for dinner apparently. ...

 

Thursday, March 6, 2014

 

TEXAS RECALL LIST MASSIVE FROM DEAD STOCK DOWNER CANCER COWS OFFAL from Class I Recall 002-2014 and 013-2014 Health Risk: High Jan 13, 2014 and Feb 8, 2014 shipped to Texas, Florida, and Illinois UPDATE FEBRUARY 14, 2014

 


 

Family hallucinates after eating LSD-tainted meat

 

By Jenn Harris This post has been corrected. See note below for details. March 10, 2014, 11:59 a.m.

 

Police are investigating an incident involving a Tampa, Fla., family who reported having hallucinations after eating meat found to be tainted with LSD last week.

 

The family of four, including Rosado Morales, who was nine months pregnant, and husband Ronnie Morales bought the packaged bottom round steak, supplied by Cargill, from a Wal-Mart in Tampa.

 

The family of four, including Rosado Morales, who was nine months pregnant, and husband Ronnie Morales bought the packaged bottom round steak, supplied by Cargill, from a Wal-Mart in Tampa.

 


 

 

kind regards,

terry
Posted by at

No comments:

Post a Comment

Subscribe to: Post Comments (Atom)